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Cremophor EL

General Information

  • Product Name: Cremophor EL
  • CAS: 61791-12-6
  • Catalog: SUR-NON-028
  • Type: EL-10, EL12, EL-20, HEL-20, EL-30, EL-40, HEL-40, EL-60, EL-80, EL-90
  • Applications: Pharmaceuticals, cosmetics, agrochemicals, textiles, others

Introduction

Cremophor EL, also known as polyoxyethylene castor oil, is a pivotal nonionic surfactant. Derived from ethoxylated castor oil, Cremophor EL possesses unique chemical properties that contribute to its widespread use in pharmaceuticals, cosmetics, agrochemicals, textiles, and beyond.

Basic Parameters

TypeAppearance 25 °CSaponification Value
(mgKOH/g)
Cloud Point
(1% aqueous)
Moisture (%)pH
(1% aqueous)
HLB
EL-10Pale yellow oil110-130--≤ 1.05.0-7.06-7
EL-12Pale yellow oil110-120--≤ 1.05.0-7.06.5-7.5
EL-20Pale yellow oil90-100≤ 30≤ 1.05.0-7.09-10
HEL-20Pale yellow oil90-100--≤ 1.05.0-7.09-10
EL-30Pale yellow oil or paste70-80≥ 45≤ 1.05.0-7.011.5-12.5
EL-40Pale yellow oil or paste57-6770-84≤ 1.05.0-7.013-14
HEL-40Pale yellow oil or paste57-67--≤ 1.05.0-7.013-14
EL-60Pale yellow paste or solid--85-90≤ 1.05.0-7.014-15.5
EL-80Pale yellow solid--≥ 91≤ 1.05.0-7.015.5-16.5
EL-90Pale yellow solid30-40--≤ 1.05.0-7.0~17

* Typical values (not warranted values); HEL — hydrogenated castor oil

Characteristics and Applications

EL-10
EL-12
EL-20
HEL-20
  • These substances dissolve in most organic solvents and disperses in water, exhibiting excellent emulsifying and dispersing properties.
  • In the textile industry, it is a key component in spinning oils for synthetic fibers like polyester and polyacrylonitrile, offering emulsification and antistatic benefits, softening, and reducing yarn breakage. HEL-20 also has low coking at high temperatures.
  • In pharmaceuticals, it serves as an emulsifier in ointments, creams, and emulsions.
  • Additionally, it acts as an emulsifier for pesticides, emulsion polymerization, water-soluble metal cutting fluids, and household cleaning products, enhancing stability and performance.
EL-30
EL-40
HEL-40
  • EL-30, EL-40, and HEL-40 dissolve easily in water, fatty acids, and organic solvents, with excellent emulsifying properties.
  • They are used as emulsifiers in inks, pharmaceuticals, and organophosphate pesticides. As o/w emulsifiers, they emulsify various vegetable, animal, and mineral oils.
  • EL-40 is used in the textile industry for wool, wool oil, and synthetic fiber oils, offering emulsifying and antistatic effects, and reducing foam in slurries. EL-40 also has excellent dispersing and colloidal protection, is easy to wash out, and resistant to hard water.
  • Additionally, it is used in crude oil dehydration, metal cutting fluids, and HEL-40 as a pharmaceutical solubilizer.
EL-60
  • EL-60 is an o/w emulsifier used in synthetic fiber and wool oils, pesticides, crude oil dehydration, inks, and printing pastes.
  • It emulsifies various oils, serves in cosmetics and pharmaceuticals as an emulsifier, fattening, and moisturizing agent, and is used in shampoos, skincare products, and metal cutting fluids.
EL-80
  • EL-80 stands out for its exceptional emulsifying properties and compatibility with fatty acids and organic solvents.
  • In the textile industry, it is utilized in synthetic fiber oils like acrylic and polypropylene, imparting antistatic effects and enhancing fiber smoothness.
  • Moreover, EL-80 finds application as a crude oil demulsifier in the oil industry, facilitating the separation of water from crude oil during refining processes.
EL-90
  • EL-90 exhibits versatile characteristics, soluble in both water and most organic solvents.
  • In the pharmaceutical sector, it serves as a multifunctional excipient, contributing to the solubilization and stability of poorly soluble drugs.
  • Additionally, EL-90 finds utility in the textile industry as a leveling agent and dispersant, ensuring uniform dyeing processes and enhancing fabric quality.

Packaging and Storage

  • Packaging Options: Typically packaged in 200 kg iron drums or 50 kg plastic drums.
  • Storage Conditions: Stored in a cool, dry place, away from direct sunlight and moisture.
  • Shelf Life: 2 years

Cremophor EL stands as a versatile and indispensable surfactant in the global market, catering to diverse industries including pharmaceuticals, cosmetics, agrochemicals, textiles, and beyond. Contact Alfa Chemistry today to learn more about our products and how they can benefit your applications.

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