Wang, Wen-Yi, et al. Polymers. 2021;13(13):2122.
Antibacterial mechanism of PHMB
Polyhexamethylene biguanide hydrochloride (PHMB) is composed of repeating biguanide units separated by hydrophobic hexamethylene hydrocarbon chains. The antibacterial mechanism of PHMB is highly dependent on the cationic biguanide group that can interact with the negatively charged phosphate headgroups on the bacterial cell membrane, ultimately leading to cell death.
PHMB coating treatment
Add 10% (w/v) PHMB, 5% (w/v) PEG400 and 8% (w/v) binder to deionized water. The fabric samples were processed using the pad-drying method. First fill the fabric sample with a finishing solution with a wet dye pick-up rate of 80%. The samples were then dried in an oven at 90°C for 5 min and then cured at a temperature of 130°C for 45 s.
Antibacterial effect
The anti-virus analysis results showed that the eradication rate of the PHMB treated polyurethane fabric against coronavirus could reach 99% within 2 hours, suggesting that the PHMB treated polyurethane fabric could be used to develop anti coronavirus clothing to curb the spread of COVID-19 in high-risk places.
