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Polyglycerol

Catalog Number
ACM9041070-1
CAS
9041-07-0
Structure
IUPAC Name
3-[3-[3-[3-[3-[3-[3-[3-[3-(2,3-Dihydroxypropoxy)-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]propane-1,2-diol
Synonyms
1,2,3-Propanetriol, homopolymer
Molecular Weight
758.8
Molecular Formula
C30H62O21
Canonical SMILES
C(C(COCC(COCC(COCC(COCC(COCC(COCC(COCC(COCC(COCC(CO)O)O)O)O)O)O)O)O)O)O)O
InChI
WOKDXPHSIQRTJF-UHFFFAOYSA-N
InChI Key
InChI=1S/C30H62O21/c31-1-21(33)3-43-5-23(35)7-45-9-25(37)11-47-13-27(39)15-49-17-29(41)19-51-20-30(42)18-50-16-28(40)14-48-12-26(38)10-46-8-24(36)6-44-4-22(34)2-32/h21-42H,1-20H2
Active Content
75%
Physical State
Liquid
Typical Applications
Humectant
Spec Sheet
Case Study

Polyglycerol Treatment to Enhance the Cycle Performance of Lithium-Sulfur Batteries

Polyglycerol Treatment to Enhance the Cycle Performance of Lithium-Sulfur Batteries Yoshida, Luna, et al. Electrochimica Acta 429 (2022): 141000.

Polyglycerol has been utilized to improve the cycle stability and performance of lithium-sulfur (Li-S) batteries by modifying microporous carbon as a host material for sulfur. In Li-S batteries, lithium polysulfide (Li2Sn) dissolves into the electrolyte during charge-discharge cycles, leading to capacity loss and poor cycle stability. To address this issue, microporous carbon materials were treated with polyglycerol to enhance their ability to host sulfur and suppress the dissolution of Li2Sn.
The modified microporous carbon, when used in sulfur cathodes, demonstrated an improvement in capacity retention. Specifically, the discharge capacity at the 50th cycle, divided by the discharge capacity at the 2nd cycle, increased from 57.6% to 75.2% with polyglycerol treatment. Fourier-transform infrared (FTIR) spectroscopy analysis confirmed that the polyglycerol treatment effectively inhibits the dissolution of Li2Sn, thereby enhancing the overall performance and cycle life of the Li-S battery.
This method of polyglycerol treatment presents a promising approach to improving the commercial viability of Li-S batteries, offering a cost-effective solution to address the challenges associated with polysulfide dissolution and ensuring better long-term cycling stability.

Polyglycerol-10 (PG-10) as a Key Reagent for the Synthesis of PPI-PG Conjugate Particles

Polyglycerol-10 (PG-10) as a Key Reagent for the Synthesis of PPI-PG Conjugate Particles Wang, Yijie, et al. International Journal of Biological Macromolecules 269 (2024): 131797.

Polyglycerol-10 (PG-10) was utilized in the synthesis of polyglycerol aldehydes and subsequently in the preparation of pea protein isolate-polyglycerol (PPI-PG) conjugate particles through a Schiff-base reaction. Initially, PG-10 was oxidized using sodium periodate in an aqueous solution, creating polyglycerol aldehydes, which were purified by dialysis. This aldehyde solution was then reacted with pea protein isolate (PPI) under basic conditions (pH 12) at elevated temperature (80°C) to form the PPI-PG conjugates.
Three different conjugates were prepared based on varying mass ratios of PG-10 to PPI, resulting in PPI-PG-0.5, PPI-PG-1, and PPI-PG-2. After the reaction, unreacted PPI was removed by centrifugation, and the conjugate dispersion was dialyzed to remove excess salts and unreacted components. The final product, PPI-PG conjugate particles, was obtained as a pale-yellow solid after freeze-drying.
The synthesis of PPI-PG conjugates demonstrates the potential of PG-10 as a versatile reagent in protein modification, enhancing the stability and functionality of biopolymer-based Pickering emulsions. The conjugates prepared using PG-10 may offer improved stability in response to pH, ion concentration, and temperature changes, addressing common challenges in biopolymer emulsions.

Polyglycerol as a Modifier in the Synthesis of Hyaluronic Acid-Conjugated Tungsten Oxide for Tumor Targeting Applications

Polyglycerol as a Modifier in the Synthesis of Hyaluronic Acid-Conjugated Tungsten Oxide for Tumor Targeting Applications Li, Ying, et al. Materials Today Communications 34 (2023): 105139.

Polyglycerol (PG) was used as a key modifier in the synthesis of a hyaluronic acid-conjugated tungsten oxide (WOx-PG-HA) system, aiming to improve water solubility and enhance tumor cell targeting. The process began with the synthesis of tungsten oxide (WOx) by reacting tungsten chloride with triethylene glycol, followed by a precipitation and washing procedure. To improve its solubility and biocompatibility, WOx was then dissolved in polyglycerol and heated at 105°C for 24 hours, forming a WOx-PG solution.
The WOx-PG solution was further functionalized by reaction with succinic anhydride in pyridine, producing a carboxyl-functionalized WOx-PG-COOH. This carboxylated compound was then activated using EDC/NHS coupling reagents, followed by reaction with ethylenediamine to yield WOx-PG-NH2. The final step involved conjugating WOx-PG-NH2 with hyaluronic acid (HA) using EDC/NHS activation, forming WOx-PG-HA. This composite was purified by ultrafiltration and preserved for further use.
The resultant WOx-PG-HA system exhibited enhanced water solubility, biocompatibility, and targeting ability for tumor cells, showcasing the potential of polyglycerol as a versatile modifier in biomedical applications, particularly for targeted drug delivery and imaging.

Custom Q&A

What is the IUPAC name of Polyglycerol?

The IUPAC name of Polyglycerol is 3-[3-[3-[3-[3-[3-[3-[3-[3-(2,3-Dihydroxypropoxy)-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]-2-hydroxypropoxy]propane-1,2-diol.

What is the molecular weight of Polyglycerol?

The molecular weight of Polyglycerol is 758.8.

What is the molecular formula of Polyglycerol?

The molecular formula of Polyglycerol is C30H62O21.

Can you provide the SMILES notation for Polyglycerol?

The SMILES notation for Polyglycerol is C(C(COCC(COCC(COCC(COCC(COCC(COCC(COCC(COCC(COCC(CO)O)O)O)O)O)O)O)O)O)O)O.

What is the CAS number for Polyglycerol?

The CAS number for Polyglycerol is 9041-07-0.

What is the InChI Key for Polyglycerol?

The InChI Key for Polyglycerol is InChI=1S/C30H62O21/c31-1-21(33)3-43-5-23(35)7-45-9-25(37)11-47-13-27(39)15-49-17-29(41)19-51-20-30(42)18-50-16-28(40)14-48-12-26(38)10-46-8-24(36)6-44-4-22(34)2-32/h21-42H,1-20H2.

What percentage of Polyglycerol is active?

75% of Polyglycerol is active.

What is the physical state of Polyglycerol?

The physical state of Polyglycerol is liquid.

What are the typical applications of Polyglycerol?

The typical applications of Polyglycerol include being used as a humectant.

What are some synonyms for Polyglycerol?

Some synonyms for Polyglycerol include 1,2,3-Propanetriol, homopolymer.

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