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Minoxidil

Catalog Number

ACM38304915

CAS

38304-91-5

Structure

IUPAC Name

3-Hydroxy-2-imino-6-piperidin-1-ylpyrimidin-4-amine

Synonyms

2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide;Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide

Molecular Weight

209.25

Molecular Formula

C9H15N5O

Canonical SMILES

C1CCN(CC1)C2=NC(=N)N(C(=C2)N)O

InChI

ZIMGGGWCDYVHOY-UHFFFAOYSA-N

InChI Key

InChI=1S/C9H15N5O/c10-7-6-8(12-9(11)14(7)15)13-4-2-1-3-5-13/h6,11,15H,1-5,10H2

Boiling Point

348.5 °C

Melting Point

272-274 °C(lit.)

Flash Point

166.5ºC

Density

1.165g/ml

Appearance

White crystalline powder

Active Content

95%

Physical State

Solid

Typical Applications

Use as pharmaceutical ingredient.
Use as emulsifying agent, dispersing agent.
Use as antirust agent, corrosion inhibitor.

MSDS

Download MSDS

COA

Download COA

Spec Sheet

Download Spec Sheet

Case Study

Use of Minoxidil in Hair Disorders

Use of Minoxidil in Hair Disorders Suchonwanit P,et al. Drug design, development and therapy, 2019: 2777-2786.

Minoxidil is a piperidinylpyrimidine derivative that affects hair follicle cells by promoting hair growth and reducing hair loss. The positive effect of minoxidil on hair growth is mainly due to its metabolite, minoxidil sulfate, and the enzyme responsible for this conversion is sulfotransferase, which is located in hair follicles and varies in production among individuals.
Minoxidil has been widely used to treat a variety of hair conditions, including:
· Androgenetic alopecia
· Female pattern hair loss
· Alopecia areata
· Beard enhancement
· Central centrifugal cicatricial alopecia
· Chemotherapy-induced alopecia
· Eyebrow enhancement
· Frontal fibrosing alopecia
· Monilethrix
· Loose anagen hair syndrome
· Telogen effluvium

Custom Q&A

What is the primary use of Minoxidil?

Minoxidil is primarily used as an antihypertensive vasodilator medication that slows hair loss and promotes hair regrowth in some people.

What is the molecular weight of Minoxidil?

The molecular weight of Minoxidil is 209.25.

What is the molecular formula of Minoxidil?

The molecular formula of Minoxidil is C9H15N5O.

How is Minoxidil typically available for purchase?

Minoxidil is now off-patent and available over the counter for the treatment of androgenic alopecia.

What are some synonyms for Minoxidil?

Some synonyms for Minoxidil include 2,4-Pyrimidinediamine, 6-(1-piperidinyl)-, 3-oxide and Pyrimidine, 2,4-diamino-6-piperidino-, 3-oxide.

What is the InChI Key of Minoxidil?

The InChI Key for Minoxidil is ZIMGGGWCDYVHOY-UHFFFAOYSA-N.

What is the boiling point of Minoxidil?

The boiling point of Minoxidil is 348.5 °C.

What is the physical state of Minoxidil?

Minoxidil is in a solid physical state.

What are some typical applications of Minoxidil?

Some typical applications of Minoxidil include use as a pharmaceutical ingredient, emulsifying agent, dispersing agent, antirust agent, and corrosion inhibitor.

How does Minoxidil promote hair regrowth?

Minoxidil promotes hair regrowth by slowing down the process of hair loss and improving blood flow to hair follicles.

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