L-Lysine, hydrochloride (1:1)

Catalog Number

ACM657272-1

CAS

657-27-2

Structure

IUPAC Name

(2S)-2,6-diaminohexanoic acid;hydrochloride

Synonyms

L-Lysine, monohydrochloride

Molecular Weight

182.65

Molecular Formula

C6H15ClN2O2

Canonical SMILES

C(CCN)C[C@@H](C(=O)O)N.Cl

InChI

BVHLGVCQOALMSV-JEDNCBNOSA-N

InChI Key

InChI=1S/C6H14N2O2.ClH/c7-4-2-1-3-5(8)6(9)10;/h5H,1-4,7-8H2,(H,9,10);1H/t5-;/m0./s1

Melting Point

263 °C (dec.)(lit.)

Density

1.28g/ml

Active Content

95%

5.5-6.0 (100g/l, H2O, 20°C)

Physical State

Solid

Typical Applications

Skin conditioning

MSDS

Download MSDS

COA

Download COA

Spec Sheet

Download Spec Sheet

Case Study

L-Lysine Monohydrochloride Used for Efficient L-Lysine Production via Ion Substitution Electrodialysis

L-Lysine Monohydrochloride Used for Efficient L-Lysine Production via Ion Substitution Electrodialysis Zhang, Y., Chen, Y., Yue, M., & Ji, W. (2011). Desalination, 271(1-3), 163-168.

L-Lysine monohydrochloride (L-Lys·HCl) is a widely used amino acid salt in biotechnology and pharmaceutical industries. Efficient recovery of free L-lysine from L-Lys·HCl is essential for downstream applications in food, feed, and biochemical synthesis. Recent studies have demonstrated the effectiveness of ion substitution electrodialysis (ISED) for this purpose, offering a scalable, energy-efficient, and environmentally friendly approach.
Experimental Approach:
The ISED setup consisted of two anion-exchange membranes (AEMs) and one cation-exchange membrane (CEM), separating four compartments with circulating electrolyte solutions. A constant DC voltage was applied across the electrodes to drive selective ion transport. Key process variables, including applied voltage, initial L-Lys·HCl concentration, solution pH, and temperature, were optimized.
Key Findings:
At an initial L-Lys·HCl concentration of 0.6 mol L⁻¹ and an applied voltage of 40 V, a chloride ion removal ratio of 95.6% was achieved, with a current efficiency of 20.5% and energy consumption of 9.0 kWh kg⁻¹. The initial pH of the solution was found to be critical, with maximum L-lysine recovery (93.2%) observed when the pH was adjusted to the isoelectric point (9.74). Furthermore, elevating the temperature improved ionic transport and overall process efficiency.
Conclusion:
This case study highlights L-Lysine monohydrochloride as a valuable substrate for L-lysine recovery through ion substitution electrodialysis. The method not only ensures high recovery and purity but also demonstrates potential for industrial-scale production with reduced energy input, supporting sustainable amino acid manufacturing.

❈ Please kindly note that our products are for research use only.