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4-Hydroxybenzophenone

Catalog Number

ACM1137424-2

CAS

1137-42-4

Structure

IUPAC Name

(4-hydroxyphenyl)-phenylmethanone

Synonyms

P-Benzoylphenol;Methanone, (4-hydroxyphenyl)phenyl-

Molecular Weight

198.22

Molecular Formula

HOC6H4COC6H5

Canonical SMILES

Oc1ccc(cc1)C(=O)c2ccccc2

InChI

1S/C13H10O2/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,14H

InChI Key

NPFYZDNDJHZQKY-UHFFFAOYSA-N

Boiling Point

419-420 °C(lit.)

Melting Point

132-135 °C (lit.)

Flash Point

235.4 °F

Purity

99%

Appearance

White to Light yellow to Light orange powder to crystal

Application

This product is suitable for scientific research.

Storage

2-8°C

Active Content

95%

Physical State

Solid

Typical Applications

Use as UV absorbing agent.
Use as intermediate in organic synthesis.

MSDS

Download MSDS

COA

Download COA

Spec Sheet

Download Spec Sheet

Case Study

4-Hydroxybenzophenone Exposure Inhibits Proliferation of Mouse Hippocampal Neural Stem Cells

4-Hydroxybenzophenone Exposure Inhibits Proliferation of Mouse Hippocampal Neural Stem Cells Lin, Yahang, et al. Toxicology in Vitro 82 (2022): 105367.

Exposure to 4-hydroxybenzophenone (4HBP) inhibits the viability and spheroid growth of primary mouse neural stem cells (NSCs) in vitro.
4HBP Exposure Inhibits NSC Proliferation: Primary mouse NSCs were obtained from the hippocampus of 14.5-day-old embryos and seeded into a 96-well plate containing proliferation medium. The cells were treated with a series of concentrations (EtOH, 1 nM, 10 nM, 102 nM, and 103 nM) of 4HBP for 7 days. Consistent with our previous observations, NSC spheroid formation ability was significantly impaired in the presence of 4HBP, as reflected by a marked decrease in the number of neurospheres after 7 days of culture. Additionally, NSC viability was assessed using the CCK-8 assay. 4HBP significantly inhibited the viability of mouse NSCs at concentrations within the 1 μM range. These results confirm the toxic effects of 4HBP exposure on the in vitro proliferation of NSCs.

Custom Q&A

What is the product name of the chemical with CAS number 1137-42-4?

4-Hydroxybenzophenone

What is the IUPAC name of 4-Hydroxybenzophenone?

(4-hydroxyphenyl)-phenylmethanone

What is the molecular weight of 4-Hydroxybenzophenone?

198.22

What is the appearance of 4-Hydroxybenzophenone?

White to Light yellow to Light orange powder to crystal

What is the boiling point of 4-Hydroxybenzophenone?

419-420 °C

What is the EC Number of 4-Hydroxybenzophenone?

214-507-1

What is the Beilstein REAXYS Number of 4-Hydroxybenzophenone?

777776

What is the application of 4-Hydroxybenzophenone?

Suitable for scientific research

What is the purity level of 4-Hydroxybenzophenone?

99%

What are the features and benefits listed for 4-Hydroxybenzophenone?

High quality products, fast delivery, additional products can be ordered

❈ Please kindly note that our products are for research use only.