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DL-Methionine

Catalog Number
ACM59518-1
CAS
59-51-8
Structure
IUPAC Name
2-Amino-4-methylsulfanylbutanoic acid
Synonyms
(RS)-2-Amino-3-methylthiobutansαure
Molecular Weight
149.21
Molecular Formula
C5H11NO2S
Canonical SMILES
CSCCC(C(=O)O)N
InChI
InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)
InChI Key
FFEARJCKVFRZRR-UHFFFAOYSA-N
Melting Point
284 °C (dec.)(lit.)
Purity
99%
Density
1.34 g/ml
Appearance
White powder
Storage
Powder-20°C, 3 years; 4°C, 2 years; In solvent-80°C, 6 months; -20°C, 1 month.
Active Content
95%
pH
5.4-6.1
Physical State
Solid
Typical Applications
Perfume
Spec Sheet
Case Study

DL-Methionine Used for the Preparation of Antimicrobial and Corrosion-Resistant Coatings via Electron Beam Irradiation

DL-Methionine Used for the Preparation of Antimicrobial and Corrosion-Resistant Coatings via Electron Beam Irradiation Mousaa, I. M., Gharieb S. El-Sayyad, and Mohamed Mohamady Ghobashy. Progress in Organic Coatings 166 (2022): 106824.

DL-Methionine (DLM), a sulfur-containing amino acid, has recently emerged as a sustainable additive in the development of multifunctional protective coatings. In a solvent-free formulation cured by electron beam (EB) irradiation, DLM was incorporated alongside abietic acid (AA) into epoxy acrylate-based coatings applied onto mild steel and other substrates. Upon exposure to a 10 kGy EB dose, the resulting thin films exhibited enhanced homogeneity and component dispersion, as confirmed by FTIR, SEM, and water contact angle analyses.
Electrochemical studies in both acidic (0.5 M HCl) and saline (3.5% NaCl) environments revealed that DLM at 0.8 wt% significantly enhances corrosion resistance, with an inhibition efficiency of 73.70% in HCl and 55.00% in NaCl. The protective mechanism involves the uniform distribution of DLM within the EB-cured matrix, which enhances adhesion and reduces electrochemical degradation at defect sites.
Beyond corrosion resistance, DL-methionine also imparts robust antimicrobial and antibiofilm properties. The D1.6 formulation demonstrated strong inhibition against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans, with inhibition zones ranging from 10.2-13.4 mm. Notably, antibiofilm activity exceeded 75% against key pathogens, indicating its dual role as a bioactive and barrier-forming agent.
These findings underscore DL-methionine's utility in high-performance coating systems for metal protection, offering a bio-derived, environmentally friendly alternative for integrated antimicrobial and anticorrosive applications.

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