What is dextran derived from?
Dextran is derived from the condensation of glucose, originally derived from wine.
How does IUPAC define dextrans?
IUPAC defines dextrans as branched poly-α-d-glucosides of microbial origin with glycosidic bonds predominantly C-1 → C-6.
What are the lengths of dextran chains?
Dextran chains can vary in length from 3 to 2000 kilodaltons.
What is the main chain of the dextran polymer composed of?
The main chain of the dextran polymer is composed of α-1,6 glycosidic linkages between glucose monomers.
How is dextran different from dextrin?
Dextran is characterized by its branching structure with α-1,3 linkages, while dextrin is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages.
Which bacteria are involved in the production of dextran?
Dextran is produced from sucrose by certain lactic acid bacteria, including Leuconostoc mesenteroides and Streptococcus mutans.
What are the medicinal uses of dextran?
Dextran is used medicinally as an antithrombotic, to reduce blood viscosity, and as a volume expander in hypovolaemia.
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