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Dextran

Catalog Number
ACM9004540
CAS
9004-54-0
IUPAC Name
2,3,4,5-Tetrahydroxy-6-[3,4,5-trihydroxy-6-[[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxyhexanal
Synonyms
Rheopolyglucine
Molecular Weight
396.43
Molecular Formula
C17H32O10
Canonical SMILES
C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC(C(C(C(C=O)O)O)O)O)O)O)O)O)O)O)O
InChI
InChI=1S/C18H32O16/c19-1-5(21)9(23)10(24)6(22)3-31-17-16(30)14(28)12(26)8(34-17)4-32-18-15(29)13(27)11(25)7(2-20)33-18/h1,5-18,20-30H,2-4H2
InChI Key
FZWBNHMXJMCXLU-UHFFFAOYSA-N
Melting Point
483 °C
Purity
98%
Appearance
White to off-white solid
Application
Dextran is a versatile polysaccharide primarily used for its water-binding properties and ability to control product viscosity. Produced by certain bacteria through the fermentation of sucrose, dextran serves multiple purposes, including acting as a thickening agent and a stabilizer in foods like ice cream. It also finds medical applications, such as being a plasma substitute in blood transfusions due to its osmotic effects, which help manage fluid balance within the bloodstream. Moreover, dextran is known to enhance the anti-aging activity of formulations with weak acids while reducing associated skin irritation. Despite these benefits, dextran, as a bacterial product, may potentially act as an antigen and pose a risk of anaphylaxis, warranting careful use in various formulations.
Storage
Store at room temperature
Active Content
80%
Physical State
Solid
Typical Applications
Use as dispersing agent, emulsifying agent.
Use as film-forming agent.
Use as thickening agent.
Use as sustained-release agent.
Use as adhesive.
Use as suspending agent.
Spec Sheet
Custom Q&A

What is dextran derived from?

Dextran is derived from the condensation of glucose, originally derived from wine.

How does IUPAC define dextrans?

IUPAC defines dextrans as branched poly-α-d-glucosides of microbial origin with glycosidic bonds predominantly C-1 → C-6.

What are the lengths of dextran chains?

Dextran chains can vary in length from 3 to 2000 kilodaltons.

What is the main chain of the dextran polymer composed of?

The main chain of the dextran polymer is composed of α-1,6 glycosidic linkages between glucose monomers.

How is dextran different from dextrin?

Dextran is characterized by its branching structure with α-1,3 linkages, while dextrin is a straight chain glucose polymer tethered by α-1,4 or α-1,6 linkages.

Which bacteria are involved in the production of dextran?

Dextran is produced from sucrose by certain lactic acid bacteria, including Leuconostoc mesenteroides and Streptococcus mutans.

What are the medicinal uses of dextran?

Dextran is used medicinally as an antithrombotic, to reduce blood viscosity, and as a volume expander in hypovolaemia.

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