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Fan, Jingbiao, et al. Soil and Tillage Research 248 (2025): 106459.
Calcium lactate (CL), an organic calcium salt, has demonstrated significant efficacy as a sustainable soil amendment for remediating saline-alkali soils. This study evaluated the influence of CL on soil salinity, alkalinity, colloid morphology, and physicochemical properties compared to conventional inorganic calcium salts such as CaCl₂ and gypsum.
CL mitigates soil salinization primarily through acid-base neutralization, reacting with excess carbonate ions (CO₃²⁻) to reduce soil alkalinity. Additionally, CL enhances cation exchange capacity by introducing Ca²⁺ ions, which effectively displace sodium (Na⁺) ions bound to soil particles. This ion exchange lowers the exchangeable sodium percentage, a critical indicator of soil sodicity, thereby improving soil structure and permeability.
Morphological analysis showed that CL supports the formation of stable soil aggregates via calcium bridging and hydrogen bonding, facilitating stronger organic-mineral interactions. These structural improvements not only reduce soil dispersion but also increase carbon retention and overall fertility. Among all amendments tested, CL displayed superior performance in balancing soil pH, reducing salinity, and enhancing aggregate stability.
In comparison to inorganic calcium sources, calcium lactate offers a more environmentally benign and biologically compatible alternative. Its dual role in chemical remediation and structural enhancement makes CL a promising candidate for sustainable agricultural practices aimed at restoring saline-alkali soils and safeguarding crop productivity.
Li, Canying, et al. Postharvest Biology and Technology 216 (2024): 113053.
Calcium lactate has shown strong potential as a postharvest treatment to delay senescence and maintain fruit quality in 'Jinfeng' pears by modulating fatty acid metabolism during ambient storage. In this study, pears immersed in 5.0 g L⁻¹ calcium lactate solution for 10 minutes exhibited significantly reduced malondialdehyde content, respiration rate, weight loss, and ethylene production compared to untreated controls.
Calcium lactate notably suppressed the activity of lipid-degrading enzymes including phospholipase D (PLD), lipoxygenase (LOX), lipase (LPS), hydroperoxide lyase (HPL), alcohol dehydrogenase (ADH), and alcohol acyltransferase (AAT). Simultaneously, it downregulated the expression of genes associated with fatty acid degradation (PcLOX, PcPLD, PcACD, PcECH, PcACOX3), while upregulating genes involved in fatty acid biosynthesis (PcACC, PcFabG, PcFabI, PcFabZ, PcKASII, PcACP, PcFAD) and elongation (PcKCS4, PcKCS6, PcKCS7, PcKCS10, PcLACS2, PcLACS4, PcLACS8, PcCER).
Metabolically, calcium lactate treatment led to a reduction in palmitic acid content and enhanced levels of linolenic, linoleic, and oleic acids, promoting membrane stability and delaying senescence.
These findings highlight calcium lactate as an effective and safe postharvest preservative, capable of extending shelf life and preserving the nutritional and sensory quality of fruit through comprehensive modulation of lipid metabolic pathways.
Hwang, Tae In, et al. Carbohydrate polymers 212 (2019): 21-29.
Calcium lactate (CaL) has been successfully employed in the fabrication of bioactive polycaprolactone (PCL)-based nanofibrous scaffolds for tissue engineering applications. In this innovative study, a dual-channel strategy was developed wherein both cellulose and CaL were regenerated in situ within electrospun PCL/cellulose acetate (CA)/lactic acid (LA) composite fibers via post-treatment with calcium hydroxide solution.
During the process, CA and LA were converted into cellulose and calcium lactate, respectively. The regenerated cellulose provided structural reinforcement, while CaL functioned as a bioactive molecule enhancing scaffold biofunctionality. The resulting PCL/Cellulose/CaL composite nanofibers exhibited significantly improved physicochemical properties, including enhanced surface wettability and mechanical strength, attributed to the formation of inter- and intramolecular hydrogen bonds among hydroxyl groups of cellulose and CaL.
Field-emission scanning electron microscopy (FESEM), infrared spectroscopy (IR), and thermal analyses (TGA/DSC) confirmed the morphological integrity and successful incorporation of CaL and cellulose into the nanofibers. Functionally, the PCL/Cellulose/CaL scaffold demonstrated excellent hydroxyapatite nucleation capability in simulated body fluid (SBF), along with enhanced cell adhesion, spreading, and proliferation-key indicators of biocompatibility.
This study showcases calcium lactate as a valuable additive in biofunctional scaffold design, enabling simultaneous structural and biological enhancement of synthetic polymer systems. The PCL/Cellulose/CaL scaffold holds great promise for regenerative medicine and tissue engineering applications.
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