Artemisia Vulgaris Extract

Catalog Number

ACM84775451-1

CAS

84775-45-1

Synonyms

Artemisia vulgaris, ext

Active Content

90%

Physical State

Solid

Typical Applications

Use as antioxidant.
Use as antibacterial agent.

MSDS

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COA

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Spec Sheet

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Case Study

Artemisia vulgaris Leaves Extract (AVLE) Used for the Green Synthesis of Bioactive Silver Nanoparticles

Artemisia vulgaris Leaves Extract (AVLE) Used for the Green Synthesis of Bioactive Silver Nanoparticles Rasheed, Tahir, et al. Colloids and Surfaces B: Biointerfaces 158 (2017): 408-415.

Artemisia vulgaris leaves extract (AVLE) has demonstrated exceptional potential as a green reducing and capping agent for the eco-friendly synthesis of silver nanoparticles (AgNPs). In a solvent-free and cost-effective approach, methanolic AVLE was combined with silver nitrate solutions (20-100 mM) to facilitate the in-situ reduction of Ag⁺ to Ag⁰ under mild stirring and room-temperature incubation. The formation of blackish-brown colloidal dispersions and the appearance of a characteristic surface plasmon resonance peak at ~420 nm confirmed successful nanoparticle synthesis.
Comprehensive characterization using UV-vis spectroscopy, SEM, TEM, EDX, AFM, and FTIR established the spherical morphology, average particle size (~25 nm), elemental silver content, and functional group involvement in nanoparticle formation. Importantly, AVLE-derived AgNPs (AV-AgNPs) exhibited superior antibacterial activity against multiple pathogenic strains compared to the plant extract alone. In vitro antioxidant assays further demonstrated significant free radical scavenging ability, while cytotoxic studies revealed potent antiproliferative effects against HeLa and MCF-7 cancer cell lines.
These findings emphasize the multifunctional bioactivity of AV-AgNPs synthesized using Artemisia vulgaris leaves extract. The method provides a sustainable, scalable, and non-toxic alternative to conventional chemical routes, offering valuable applications in antimicrobial therapy, cancer treatment, and oxidative stress mitigation. This work highlights AVLE as a powerful phytochemical resource for the synthesis of next-generation nanomaterials in biomedical research.

Artemisia vulgaris L. Leaf Extract Used for the Green Synthesis of Larvicidal Gold Nanoparticles Against Aedes aegypti

Artemisia vulgaris L. Leaf Extract Used for the Green Synthesis of Larvicidal Gold Nanoparticles Against Aedes aegypti Sundararajan, B., and BD Ranjitha Kumari. Journal of Trace Elements in Medicine and Biology 43 (2017): 187-196.

Artemisia vulgaris L. leaf extract has proven to be an effective green reducing agent for the eco-friendly biosynthesis of gold nanoparticles (AuNPs), offering a novel strategy for mosquito vector control. In this study, 10 mL of A. vulgaris extract was reacted with 1 mM aqueous HAuCl₄, forming AuNPs within 20 minutes at room temperature, indicated by a characteristic purple-red color shift due to Au³⁺ reduction.
The synthesized AuNPs were characterized using UV-Vis, XRD, FTIR, DLS, Zeta Potential, TEM, EDX, and solid-state ¹³C NMR, which confirmed the presence of β-caryophyllene-an active larvicidal component-embedded in the nanoparticles. Larvicidal assays demonstrated that the AuNPs displayed superior toxicity against Aedes aegypti larvae compared to the essential oil alone. After 24 hours, the LC₅₀ values of the AuNPs were significantly lower for both 3rd (62.47 ppm) and 4th instar larvae (43.01 ppm), indicating enhanced efficacy.
Histopathological analysis revealed severe damage in the midgut and epithelial tissues of larvae exposed to AuNPs, confirming their potent biological activity. These findings underscore the potential of A. vulgaris L. leaf extract-mediated AuNPs as a cost-effective, sustainable nanobiopesticide to combat dengue fever by targeting its primary vector, A. aegypti. This green synthesis route integrates plant bioactives with nanotechnology to deliver a powerful solution for public health applications.

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