Permyakova, N. M., et al. Applied Nanoscience 12.4 (2022): 1295-1313.
Alpha-tocopheryl acetate, a lipid-soluble and pharmacologically active vitamin E derivative, has been successfully incorporated into double hydrophilic diblock copolymer micelles for use in veterinary drug delivery systems. These micelles, composed of methoxypoly(ethylene oxide) and poly(acrylic acid), self-assemble in aqueous solutions at pH < 5 to form distinct "cut" and "hairy" structures with a complex core capable of encapsulating hydrophobic compounds.
When applied to deliver α-tocopheryl acetate, these micellar carriers demonstrated remarkable properties-non-toxicity, biodegradability, biocompatibility, and high stability over a wide pH range (3.5-9.0) and in physiological media. Particularly, the "hairy" micelles, due to their extended polyacrylic acid segments, offered superior protection against salting-out effects and sustained drug release under concentration gradient conditions.
In vivo studies on sows confirmed the efficacy of these micellar formulations as dietary supplements. The delivery system enhanced metabolic activity in sows, improved reproductive performance, and increased both stress resistance and survival rates of piglets.
This study highlights the advanced application of α-tocopheryl acetate in animal nutrition via nanocarrier-mediated delivery systems, establishing its value as a potent micronutrient supplement when formulated using smart polymeric materials tailored for biological stability and controlled release.
Pérez, Eduardo, et al. Industrial & engineering chemistry research 49.18 (2010): 8495-8500.
Alpha-tocopheryl acetate, a stable esterified form of vitamin E, plays a crucial role in the fabrication of advanced functional materials through its encapsulation into porous carriers. In a recent study, an efficient encapsulation methodology was developed to embed α-tocopheryl acetate into zeolite Y, enabling its incorporation into polyamide-6 fibers for industrial textile applications.
The process begins with thermal activation of zeolite Y at 250 °C for 24 hours to enhance its surface activity. Subsequently, a 3:1 weight ratio of α-tocopheryl acetate to zeolite Y is mixed under vigorous stirring at 110 °C for 24 hours to facilitate sorption and entrapment. After encapsulation, the zeolite microcapsules are separated via water decantation, and unencapsulated α-tocopheryl acetate is recovered for reuse.
Post-processing includes drying at 80 °C for 12 hours, followed by grinding and micronization to achieve a fine particle size of 1-2 µm. These vitamin E-loaded microcapsules are then blended into polyamide-6 during fiber spinning at a dosage of 0.37 g per 100 g of polymer, resulting in high-performance fibers with antioxidant functionality.
This case study demonstrates that α-tocopheryl acetate serves as a key active agent in the production of encapsulated additives for textiles, combining nutritional benefits with material innovation for health-enhancing fiber development.
What is the chemical name of the product Alpha-Tocopheryl acetate?
The chemical name is 2H-1-Benzopyran-6-ol, 3,4-dihydro-2,5,7,8-tetramethyl-2-((4R,8R)-4,8,12-trimethyltridecyl)-, 6-acetate, (2R)-.
What is the CAS number of Alpha-Tocopheryl acetate?
The CAS number is 58-95-7.
What are some synonyms for Alpha-Tocopheryl acetate?
Some synonyms are Tocopheryl acetate, d-alpha-Tocopherol acetate, and Vitamin E acetate.
What is the molecular weight of Alpha-Tocopheryl acetate?
The molecular weight is 472.74.
What is the physical state of Alpha-Tocopheryl acetate?
It is in a liquid state.
What percentage of actives does Alpha-Tocopheryl acetate contain?
It contains 95% actives.
What is the typical application of Alpha-Tocopheryl acetate?
It is used as an antioxidant.
What is the molecular formula of Alpha-Tocopheryl acetate?
The molecular formula is C31H52O3.
How is Alpha-Tocopheryl acetate commonly used in industries?
It is commonly used in cosmetics, pharmaceuticals, and food industries.
What are the benefits of using Alpha-Tocopheryl acetate as an antioxidant?
It helps protect cells from damage, improves skin health, and supports the immune system.
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