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Adenosine

Catalog Number

ACM58617

CAS

58-61-7

Structure

IUPAC Name

(2R,3R,4S,5R)-2-(6-Aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Synonyms

Adenine-9-1'-β-ribofuranoside

Molecular Weight

267.24

Molecular Formula

C10H13N5O4

Canonical SMILES

C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)N

InChI

InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1

InChI Key

OIRDTQYFTABQOQ-KQYNXXCUSA-N

Boiling Point

410.43 °C

Melting Point

234-236 °C(lit.)

Purity

99%

Density

1.3382 g/cm³

Solubility

Soluble in water, ammonium hydroxide, dimethyl sulfoxide, insoluble in ethanol

Appearance

White crystalline powder

Storage

2-8 °C

Active Content

95%

Physical State

Solid

Typical Applications

Use as emulsion stabilizer, dispersing agent.
Use as intermediate in organic synthesis.

MSDS

Download MSDS

COA

Download COA

Spec Sheet

Download Spec Sheet

Case Study

Role Of Adenosine In The Central Nervous System

Role Of Adenosine In The Central Nervous System Dunwiddie, Thomas V., and Susan A. Masino. Annual review of neuroscience 24.1 (2001): 31-55.

Adenosine is a modulator with a general and ubiquitous inhibitory effect on neuronal activity. Tonic activation of adenosine receptors by adenosine, which is normally present in the extracellular space of brain tissue, results in an inhibitory effect that appears to be mediated by adenosine A and A receptors. Relief of this tonic inhibition by receptor antagonists is responsible for the excitatory effects of these drugs. Characterization of the actions of adenosine receptor agonists and antagonists has led to many hypotheses regarding the actions of this nucleoside.
Adenosine participates in a variety of functions in the central nervous system. Although in a general sense many of its actions are inhibitory, consistent with its role as an endogenous anticonvulsant, neuroprotectant, and sleep-inducing factor, this depends on the brain system and complement of adenosine receptors present. There is little evidence that adenosine is a neurotransmitter; rather, it appears to be a neuromodulator that is released in some unconventional manner to modulate and regulate neuronal activity. A current challenge in the field is to better define the mechanisms of adenosine release in response to both pathological and nonpathological stimuli.

Custom Q&A

What is the molecular weight of Adenosine?

The molecular weight of Adenosine is 267.24.

What is the purity of Adenosine?

The purity of Adenosine is 99%.

What is the appearance of Adenosine?

Adenosine appears as a white powder.

What are some synonyms for Adenosine?

Some synonyms for Adenosine are 9-beta-D-Ribofuranosidoadenine and 9-beta-D-Ribofuranosyl-9H-purin-6-amine.

What is the physical state of Adenosine?

The physical state of Adenosine is solid.

What are the typical applications of Adenosine?

Adenosine is used as an emulsion stabilizer and dispersing agent, as well as an intermediate in organic synthesis.

What is the CAS number of Adenosine?

The CAS number of Adenosine is 58-61-7.

What is the molecular formula of Adenosine?

The molecular formula of Adenosine is C10H13N5O4.

What is the percentage of actives in Adenosine?

The percentage of actives in Adenosine is 95%.

What is the chemical composition of Adenosine?

Adenosine is composed of carbon, hydrogen, nitrogen, and oxygen.

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