beta-Cyclodextrin

• Catalog Number: ACM7585399-3
• CAS: 7585-39-9
• IUPAC Name: (1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-5,10,15,20,25,30,35-heptakis(hydroxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontane-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecol
• Synonyms: Cycloheptapentylose
• Molecular Weight: 1135g/mol
• Molecular Formula: C42H70O35
• Canonical SMILES: C(C1C2C(C(C(O1)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)OC5C(OC(C(C5O)O)OC6C(OC(C(C6O)O)OC7C(OC(C(C7O)O)OC8C(OC(O2)C(C8O)O)CO)CO)CO)CO)CO)CO)O)O)O
• InChI: InChI=1S/C42H70O35/c43-1-8-29-15(50)22(57)36(64-8)72-30-9(2-44)66-38(24(59)17(30)52)74-32-11(4-46)68-40(26(61)19(32)54)76-34-13(6-48)70-42(28(63)21(34)56)77-35-14(7-49)69-41(27(62)20(35)55)75-33-12(5-47)67-39(25(60)18(33)53)73-31-10(3-45)65-37(71-29)23(58)16(31)51/h8-63H,1-7H2/t8-,9-,10-,11-,12-,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-/m1/s1
• InChI Key: WHGYBXFWUBPSRW-FOUAGVGXSA-N
• Boiling Point: 845°C
• Melting Point: 290-300 °C (dec.) (lit.)
• Flash Point: 908.5°C
• Density: 1.23g/ml
• Solubility: Sparingly soluble in water; freely soluble in hot water; slightly soluble in ethanol
• Appearance: White powder
• Application: Beta-Cyclodextrin serves as a versatile compound with a wide range of applications across various industries. It is a cyclic oligosaccharide derived from starch through an enzymatic conversion process, resulting in a crystalline solid or fine powder. This cyclic structure, composed of seven D-glucopyranose units, forms a toroid shape with a hydrophobic internal cavity and a hydrophilic external surface. Such an arrangement allows beta-cyclodextrin to encapsulate guest molecules, enhancing their solubility and stability. This property is particularly beneficial in pharmaceuticals, where it is employed to improve the solubility, bioavailability, and stability of poorly soluble drugs, mitigate gastrointestinal irritation, and prevent drug interactions. Despite being the least soluble cyclodextrin, it is the most widely used due to its cost-effectiveness and the ability to form inclusion complexes with a variety of molecules of pharmaceutical interest. However, its use is limited to non-parenteral formulations due to nephrotoxicity risks. Beyond pharmaceuticals, beta-cyclodextrin is utilized in food, chemical, agricultural, and environmental applications, demonstrating its broad utility in enhancing substance properties and delivery.
• Active Content: 80%
• pH: 5-8
• Physical State: Solid
• Typical Applications: Chelator; Absorbent